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左心房附属体速度,与非膜心房的患者的炎症指数的关联

Hamideh Khesali¹, Amir Ghaffari Jolfayi², Amirali Soheili²

¹Echocardiography research Center, Rajaie cardiovascular medical and research Center, Iran University of Medical Science, Tehran, Iran.

Future cardiology

|January 28, 2025

概括

在心房动 (AF) 患者中,左心房附属体排空速度 (LAAV) 的降低与大多数炎症标志物无关. 只有白细胞与血小板的比率 (WPR) 与LAAV的负相关性较弱.

科学领域:

心脏病学心脏病学
炎症研究炎症研究
血栓形成的原因是血栓形成.

背景情况:

左心房附属体排空速度 (LAAV) 的降低是心房动 (AF) 患者血栓形成风险的公认指标.
炎症过程越来越多地与心血管疾病的病理生理学有关,包括AF.

研究的目的:

调查LAAV与非膜AF患者各种炎症指数之间的关联.
为了确定常见的炎症标志物是否与减少的LAAV相关,这是血栓形成的预测因素.

主要方法:

分析了875名非膜AF患者的队列.
根据LAAV (<25厘米/秒,25-55厘米/秒,>55厘米/秒) 患者被分为三组.
包括血小板与淋巴细胞的比率,中性粒细胞与淋巴细胞的比率,全身免疫炎症指数,中性粒细胞与血小板的比率以及白细胞与血小板的比率 (WPR) 在内的炎症指数在各组之间进行了比较.

主要成果:

在LAAV组之间没有观察到大多数炎症指数的显著统计差异.
除了WPR外,没有任何评估的炎症标志物与LAAV有显著的相关性.
在WPR和LAAV之间发现了弱负相关性 (p=0.01,r=-0.10).
较低的LAAV与年龄较大,左心室喷射率降低和左心房体积指数增加有关.

结论:

这项研究发现,在非膜性AF患者中,常见的炎症指数和LAAV之间没有显著的关联.
白血细胞与血小板的比率 (WPR) 与LAAV的负相关性很弱,这表明存在潜在的,尽管很小的联系.
诸如年龄,左心室喷射率和左心房体积等因素与减少的LAAV比系统性炎症标志物更强烈相关.

关键词:

左心房附属体的速度速度.炎症指数炎症指数中性粒细胞与淋巴细胞的比率.非膜性心房动是一种非膜性心房动.血小板与淋巴细胞的比率.系统性免疫炎症指数

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