严重登革热患者的预后因素:一个多中心的回顾性队列研究
Cheng-Hsun Yang1, Ing-Kit Lee1,2, Yi-Chun Chen1,2
1Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan (R.O.C.).
PLoS neglected tropical diseases
|January 28, 2025
概括
早期识别严重登革热 (SD) 是至关重要的. 诸如老年,意识变化,胃肠道出血,白细胞病,急性损伤,严重肝炎和肺炎等因素增加了SD患者的死亡风险.
科学领域:
- 传染性疾病 传染性疾病
- 临床医学 临床医学
- 流行病学 流行病学
背景情况:
- 严重的登革热 (SD) 构成重大威胁,需要早期检测和管理,以减少死亡率.
- 了解SD死亡率的临床特征和风险因素对于有效的患者护理至关重要.
研究的目的:
- 调查诊断出严重登革热的患者的临床特征.
- 确定与严重登革热患者死亡率相关的独立风险因素.
主要方法:
- 在2002年至2019年期间,在两个医疗中心进行了一项回顾性研究.
- 分析了294名实验室证实严重登革热的成年患者的数据.
主要成果:
- 在294名严重登革热患者中,死亡率为31%.
- 死亡的独立风险因素包括老年,意识变化,胃肠道出血,白细胞病,急性损伤,严重肝炎和肺炎.
- 器官功能障碍,如急性损伤,严重肝炎和肺炎,与增加的死亡风险有显著联系.
结论:
- 对于一线医生来说,早期识别高死亡风险的严重登革热患者至关重要.
- 根据已识别的风险因素及时实施干预措施,可以显著减少严重登革热死亡人数,并改善患者的治疗结果.
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