低剂量和超低剂量腹部CT与深度学习重建和标准剂量腹部CT使用双分割扫描之间的图像质量的内部比较.
Tae Young Lee1, Jeong Hee Yoon, Jin Young Park
1From the Department of Radiology, Ulsan University Hospital, Ulsan, Republic of Korea (T.Y.L.); Department of Radiology, University of Ulsan College of Medicine, Seoul, Republic of Korea (T.Y.L.); Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea (J.H.Y., H.K., J.M.L.); Department of Radiology, Seoul National University College of Medicine, Seoul, Republic of Korea (J.H.Y., S.H.P., J.M.L.); Department of Radiology, Inje University Busan Paik Hospital, Busan, Republic of Korea (J.Y.P.); Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea (S.H.P.); Department of Radiology, Hanyang University College of Medicine, Seoul, Republic of Korea (C.L.); Division of Biostatistics, Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Republic of Korea (Y.C.); and Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Republic of Korea (J.M.L.).
与基于模型的代重建 (MBIR) 的标准剂量CT相比,低剂量和超低剂量计算机断层扫描 (CT) 与深度学习重建 (DLR) 证明了非较低的焦点肝损伤 (FLL) 显著性和检测. 然而,潜在的转移检测灵敏度下降需要谨慎.
科学领域:
- 放射学 放射学是一门学科.
- 医疗成像医学成像
- 在瘤学瘤学.
背景情况:
- 焦点肝病变 (FLLs) 需要准确的检测和表征.
- 标准剂量计算机断层扫描 (CT) 提供了良好的图像质量,但涉及更高的辐射暴露.
- 深度学习重建 (DLR) 提供了在降低辐射剂量下改善图像质量的潜力.
研究的目的:
- 为了在低剂量和超低剂量CT与DLR和标准剂量CT与基于模型的代重建 (MBIR) 之间进行个体内比较,来比较FLLs的明显性.
- 评估降低剂量CT技术用于检测肝转移的非劣势性.
- 评估DLR对疑似肝转移的图像质量和病变检测的影响.
主要方法:
- 前性研究比较双源CT扫描与剂量分割 (67%低剂量,33%超低剂量) 使用DLR与标准剂量 (100%) MBIR.
- 三名放射科医生使用利克特尺度和定量比率评估了FLL显著性,转移概率和图像质量.
- 对于明显性 (-0.5) 和检测性 (-0.1) 设置了非劣势边际.
主要成果:
- 通过低剂量和超低剂量CT,可以实现减少辐射剂量 (3.75/1.87 mGy vs 5.62 mGy).
- 与标准剂量CT相比,FLL的可见性和检测率较低,但在非劣势边际内.
- 降低剂量组 (75.7%/73.7%) 与标准剂量组 (80.6%) 的肝转移敏感性较低,但特异性保持相似.
结论:
- 使用DLR的低剂量和超低剂量的CT显示,与使用MBIR的标准剂量CT相比,FLL的可见性和检测性并非劣.
- 减少的辐射剂量是可行的肝损伤评估使用DLR.
- 临床实施需要考虑观察到的转移检测灵敏度的下降.
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