评估甲状腺激发激素与手握强度和肌力衰竭在甲状腺功能良好的绝经后妇女之间的关联
Pascual García-Alfaro1, Faustino R Pérez-López2, María Angela Sulé3
1From the Department of Obstetrics, Gynecology and Reproduction, Dexeus University Hospital, Barcelona, Spain.
Menopause (New York, N.Y.)
|January 28, 2025
概括
血清甲状腺刺激激素 (TSH) 水平与手握强度 (HGS) 或肌力衰竭无关. 这一发现表明,TSH在这个人群中不是肌肉力量的预测指标.
科学领域:
- 内分泌学 在内分泌学.
- 老年学是一门学科.
- 肌肉骨健康 肌肉骨健康
背景情况:
- 甲状腺激素在新陈代谢和肌肉功能中起着至关重要的作用.
- 了解甲状腺功能和肌肉力量之间的关系对于老龄化人口来说很重要.
- 肌力衰竭,或与年龄相关的肌肉力量损失,是绝经后妇女的重大健康问题.
研究的目的:
- 为了研究血清甲状腺刺激激素 (TSH) 水平和手握强度 (HGS) 之间的关联.
- 为了检查血清TSH水平和静脉动症在euthyroid绝经后妇女之间的关系.
- 在这个人口群体中确定肌肉力量下降的潜在预测因素.
主要方法:
- 在385名甲状腺功能良好的绝经后妇女中进行了探索性横截面研究.
- 测量了血清中的TSH,HGS和动力衰竭.
- 使用了根据年龄,BMI,肥胖,身体活动和其他相关因素调整的多变量回归模型.
主要成果:
- 血清TSH水平与HGS没有显著的关联.
- 血清TSH水平和动脉缩症之间没有发现显著的关联.
- 年龄,肥胖度,BMI,淋巴膜过率和体力活动与HGS有显著的关联.
结论:
- 正常的血清TSH水平与手握强度降低或经过绝经后的女性甲状腺功能减弱的动力衰竭无关.
- 在这个人群中,TSH不太可能是肌肉力量的直接决定因素.
- 进一步的研究可能会探索其他影响肌肉力量的内分泌或代谢因素.
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