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Updated: May 30, 2025

Clonal Analysis of Embryonic Hematopoietic Stem Cell Precursors Using Single Cell Index Sorting Combined with Endothelial Cell Niche Co-culture
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解读多细胞真菌症复杂的克隆异质性和对干扰素α的反应

Milena Kalmer1,2, Martin Grasshoff3, Tiago Maié3

  • 1Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.

Blood advances
|January 28, 2025
PubMed
概括

干扰素α (IFN-α) 疗法通过诱导亡和分化来减少多细胞真菌 (PV) 克隆,特别是在具有高核糖体基因表达的细胞中. 这说明了IFN-α如何向髓增殖性瘤 (MPNs) 中的病变细胞.

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