COVID-19对甲状腺功能测试的人口水平的影响:来自重复横截面研究的结果
Gabriel Berkebile1, Françoise Barbé2, Catherine Malaplate3
1Department of Endocrinology, Diabetology, and Nutrition (EDN), University Hospital of Nancy, Nancy F-54000, France.
Journal of infection and public health
|January 28, 2025
概括
由于COVID-19大流行,甲状腺功能测试在人口水平上发生了显著的变化,显示TSH和FT3较低,FT4较高. 这些甲状腺功能测试变化与COVID-19独立相关.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 之前的报道表明COVID-19患者的甲状腺异常.
- 关于COVID-19对甲状腺功能的影响的人口级数据有限.
研究的目的:
- 评估COVID-19流行病对甲状腺功能测试的人口水平的影响.
主要方法:
- 一项重复的横截面研究将2020年3月1日至4月15日的甲状腺功能测试与2018年和2019年的同一时期进行了比较.
- 分析了3968个甲状腺功能测试.
主要成果:
- 与参考期相比,COVID-19浪潮患者的TSH和FT3水平显著降低,FT4水平更高.
- 低FT3/高FT4比率与COVID-19独立相关.
- 在COVID-19浪潮期间,同时出现FT3和FT4变化的受试者比例更高 (OR 3.62).
结论:
- COVID-19与甲状腺功能测试中的人口水平显著变化有关.
- 这些发现可能会影响COVID-19患者的管理.
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