在人类癌症中产生的PRMT5和RUVBL1突变的蛋白结构分析

Majd Al-Marrawi1, Ruben C Petreaca2, Renee A Bouley3

  • 1Neuroscience Undergraduate Program, The Ohio State University, USA.

Cancer genetics
|January 28, 2025
PubMed
概括

DNA双链断裂的修复依赖于TIP60复合体. 这项研究揭示了酵母和人类蛋白质之间的结构相似性,表明癌症突变可能会破坏这一关键的修复复合.

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