一个实用的方法来调查医院内获取阿斯伯吉洛斯的实验方法
Eelco F J Meijer1,2,3, Aleksandra Marek4,5,6, Gordon Ramage7
1Canisius-Wilhelmina Hospital (CWZ)/Dicoon, Medical Microbiology and Immunology, Nijmegen, The Netherlands.
Medical mycology
|January 28, 2025
概括
本综述概述了一种系统方法,用于在免疫功能低下的患者中调查医院性阿斯伯吉洛症 (IA). 它建议根据病例数量和医院感染的可能性进行增量反应,增强感染控制策略.
科学领域:
- 医学真菌学 医学真菌学
- 传染病流行病学 传染病流行病学
- 医院感染控制中心
背景情况:
- 侵袭性菌病 (IMD),特别是侵袭性菌病 (IA),在免疫抑制个体中构成显著的死亡风险.
- 现有的指导方针侧重于IA预防,但为应对医院病例的感染预防和控制 (IPC) 团队提供有限的指导.
- 需要一个结构化的方法来调查和管理医院获得的IA.
研究的目的:
- 描述一种系统的,以证据为基础的方法,用于调查医院病房性阿斯伯吉洛症.
- 根据医院入院以来的时间来定义可能和可能的医院获得的标准.
- 倡导根据病例数量和医院来源的可能性量身定制的增量IPC反应.
主要方法:
- 系统审查现有的指导方针和关于侵入性阿斯伯吉洛症预防和控制的文献.
- 根据住院入院时间表,制定定义医院收购的框架.
- 关于IPC调查的逐步升级战略的建议,从单个病例到疫情爆发.
主要成果:
- 提出了一个框架,以根据入院后的几天来区分可能的和可能的医院IA.
- 建议采用分层调查策略,从监测开始,然后继续进行环境控制,监测和基因定型.
- 建议包括检查建筑工地和审查在爆发场景中的抗真菌预防.
结论:
- 实施一个系统的,渐进的方法来调查医院AI可以改善IPC团队的反应.
- 加强监测和环境评估对于控制医疗保健机构的IA爆发至关重要.
- 加强监测系统对于了解和减轻侵入性阿斯伯吉洛症的流行病学至关重要.
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