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Updated: May 30, 2025

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调节Nrf2活性:在氧化回归稳定中,泛素酶和信号分子在氧化回归稳定中起作用

John D Hayes1, Sharadha Dayalan Naidu1, Albena T Dinkova-Kostova1

  • 1Jacqui Wood Cancer Centre, Division of Cancer Research, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK.

Trends in biochemical sciences
|January 28, 2025
PubMed
概括

转录因子Nrf2对于细胞防御至关重要,由E3无素连接酶调节. 这些酶控制Nrf2的稳定性,影响细胞对氧化应激的反应,并维持平衡.

关键词:
这就是 KEAP1 的特点.这就是NRF2的NRF2.在SQSTM1/p62中使用.氧化还原开关的还原开关.信号传输,信号传输.这就是β-TrCP.

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