严重的消化障碍对皮肤内镜胃口术后的整体存活率的影响
Kazumi Shimamoto1, Ryota Matsui2,3, Yorihiro Nishiyama4
1Department of Gastroenterology, Omi Medical Center, 1660 Yabase-cho, Kusatsu, 525- 8585, Shiga, Japan. shimamoto4164@gmail.com.
Scientific reports
|January 28, 2025
概括
在经过皮肤内镜胃口术 (PEG) 的患者中,严重的消化不良显著恶化了生存率. 这种情况是一个独立的不良预后因素,吸入性肺炎是死亡的常见原因.
科学领域:
- 胃肠病学 胃肠病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 在瘤学瘤学.
背景情况:
- 消化不良或吞困难是各种疾病的常见并发症.
- 穿皮内镜胃口术 (PEG) 经常用于为患有失消症的患者提供营养支持.
- 在PEG安置后,缺食症严重程度对生存结果的影响需要进一步阐明.
研究的目的:
- 在接受PEG.的患者中调查严重的消化不良和整体存活率之间的关联.
- 为了确定影响这种患者队列生存的预后因素.
主要方法:
- 在2016年4月至2021年4月期间接受PEG治疗的107名患者的回顾性分析.
- 使用Hyodo-Komagane评分通过内镜评估吞功能.
- 患者分为中度 (得分 ≤ 8) 和严重 (得分 ≥ 9) 缺食症组.
- 作为主要结果的整体存活率,使用多变量Cox比例危险模型进行分析.
主要成果:
- 严重的失消症组 (47名患者) 与中度失消症组 (60名患者) 相比,整体存活率明显降低 (p < 0.0001).
- 严重的消化不良被确定为一个独立的不良预后因素 (危险比: 2.956,p < 0.001).
- 与吸气相关的肺炎是PEG后最常见的死亡原因.
结论:
- 在接受PEG的患者中,严重的消化障碍是预后不佳的重要独立预测因素.
- 临床评估和治疗严重的消化障碍对于改善PEG患者的生存结果至关重要.
- 进一步研究干预措施以减轻与失消症相关的死亡率是有必要的.
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