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Updated: May 30, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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突变p53通过一种与野生类型共享的基因占用模式来调节一个独特的基因组

Ramy Rahmé1,2,3, Lois Resnick-Silverman1, Vincent Anguiano1,4

  • 1Department of Oncological Sciences and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

EMBO reports
|January 28, 2025
PubMed
概括

突变p53和Mdm2令人惊的是增强野生型p53与DNA的结合,而不仅仅是抑制它. 这种相互作用会影响基因表达和细胞对辐射的反应.

关键词:
骨髓 骨髓 骨髓 骨髓 骨髓DNA 损伤 DNA 损伤基因表达 基因表达辐射敏感性 辐射敏感性在 p53 里,p53 是一个 p53 的代码.

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