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Updated: May 30, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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双模特功能融合神经网络集成绑定站点信息用于药物标亲和力预测

Haohuai He1,2, Guanxing Chen1,2, Zhenchao Tang1,2

  • 1State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.

NPJ digital medicine
|January 28, 2025
PubMed
概括

这项研究介绍了DMFF-DTA,这是一种用于预测药物标结合亲缘关系的新型双模态神经网络. 该模型通过精确整合药物和蛋白质特征来增强药物发现,优于现有方法.

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