在芬兰,2008年至2023年双胞胎怀孕中的新生儿结局
1Institute of Clinical Medicine and Department of Pediatrics, University of Eastern Finland, Kuopio, Finland. ilari.kuitunen@uef.fi.
European journal of pediatrics
|January 28, 2025
概括
芬兰双胞胎怀孕的结果有所改善,新生儿死亡率下降. 然而,新生儿重症监护室对终身双胞胎的入院人数不断增加,需要持续监测.
科学领域:
- 围产和新生儿医学
- 公共卫生研究 公共卫生研究
- 双胞胎怀孕的流行病学
背景情况:
- 双胞胎怀孕比单胎怀孕带来更高的孕产妇和新生儿并发症风险.
- 芬兰保持着世界上新生儿死亡率最低的国家之一.
研究的目的:
- 分析2008年至2023年期间芬兰双胞胎怀孕结果的趋势.
- 评估生死胎,围产儿死亡率,新生儿死亡率,新生儿重症监护室住院率和双胞胎早期住院率的变化.
主要方法:
- 使用芬兰医疗出生登记册进行的回顾性全国性队列研究.
- 从2008年到2023年,包括23,588名双胞胎出生.
- 对围产死亡率,死胎,新生儿死亡率,新生儿重症监护室入院率和7天住院率的分析.
主要成果:
- 总体死亡出生率为9.0/1000;围产期死亡率为16.0/1000.
- 在2022-2023年,新生儿死亡率在终身 (0.9/1000) 和早产 (4.6/1000) 双胞胎中显著下降.
- 在早产双胞胎的NICU入院率稳定,但在早产双胞胎的入院率上升;7天住院率下降.
结论:
- 观察到的趋势反映了产前护理的改善以及芬兰强大的新生儿护理体系.
- 增加母亲的年龄和肥胖可能会导致长期双胞胎的NICU入院人数增加.
- 在芬兰生育率下降的情况下,对双胞胎新生儿结果的持续监测至关重要.
相关概念视频
Teratogenicity
2.3K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.3K
Oogenesis
63.4K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.4K
Nature and Nurture
20.4K
Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
20.4K


