药物分配是否会影响患者的药物知识和药物坚持? 一个系统的审查和元分析
Elizabete Priscila Costa Santana1, Haidelucia Rodrigues Vieira Javarini2, Dyego Carlos Souza Anacleto de Araújo1
1Laboratory of Innovation for Healthcare (Linc), Postgraduate Program in Pharmaceutical Sciences, Federal University of Espírito Santo, Vitória, ES, Brazil.
BMC health services research
|January 28, 2025
概括
药物发行改善了患者的药物知识,但没有显著影响药物坚持. 这一系统性审查突出了改善药物发行服务和患者结果的领域.
科学领域:
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
- 患者教育 患者教育
背景情况:
- 不充分的药物知识和不坚持有助于不利的健康结果,如治疗失败和住院.
- 药剂师主导的药物分发,包括咨询,是关键的医疗保健服务,有可能影响患者的治疗结果.
- 关于药物发行对患者药物知识和药物坚持的影响的证据仍然有限.
研究的目的:
- 系统地评估药物发行对患者药物知识的影响.
- 评估药物发行对患者药物坚持的影响.
主要方法:
- 一个全面的系统审查和对社区药房药物发行研究的元分析.
- 在主要数据库 (PubMed/Medline,BVS,Web of Science,Embase) 和灰色文献中进行的搜索.
- 包括任何设计的原始研究,通过定性合成和随机对照试验的元分析进行数据合成.
主要成果:
- 包括来自全球不同地区的11项研究,其中大多数是干预性研究.
- 所有四项评估药物知识的研究都显示药物发放后的增加.
- 对三项随机对照试验的元分析发现,在药物分配后的药物坚持方面没有统计学上显著的差异 (RR: 1.19;95%CI 0.99至1.43).
结论:
- 药物发行有效地提高了患者的药物知识.
- 目前的证据表明,药物发行不会显著影响药物服药.
- 结果支持基于证据的决策,用于公共卫生政策和干预措施,以优化药物发行实践.
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