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Updated: May 30, 2025

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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大肠杆菌细胞毒性死因子-1通过引起氧化应激,DNA损伤和肠道透性改变来促进结直肠癌发生

Michela Tozzi1, Alessia Fiore2, Sara Travaglione2

  • 1Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

Journal of experimental & clinical cancer research : CR
|January 28, 2025
PubMed
概括

来自大肠杆菌的细胞毒性死因子1 (CNF1) 毒素通过引起DNA损伤和改变肠道屏障功能来促进结直肠癌 (CRC). 这项研究证实了CNF1的存在.

关键词:
三维的Caco-2球形体.在CNF1中,CNF1是CNF1.结肠直肠癌是一种癌症.造成的DNA损伤是DNA损伤.埃舍里希亚大肠杆菌 (Escherichia coli) 是一个大肠杆菌.基因毒性 基因毒性免疫系统的透.炎症 炎症是一种炎症.肠道的透性 肠道的透性氧化应激是一种氧化应激.

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