持续性呼吸障碍后COVID-19的危险因素和预测因素:系统性审查
Sandra Morgan1, James M Smith2, Bini Thomas1
1University of South Florida, Tampa, USA.
Clinical nursing research
|January 29, 2025
概括
在COVID-19后持续性呼吸不良是常见的. 女性性别,肥胖和先前存在的疾病是关键的风险因素,使早期干预能够获得更好的结果.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 肺部病理学 肺部病理学
背景情况:
- 后COVID-19综合征经常包括持续性呼吸困难,影响26-41%的个人.
- 了解持续性呼吸困难的风险因素对于所有COVID-19严重程度的有针对性的干预至关重要.
研究的目的:
- 在COVID-19后的人群中系统地审查与持久性呼吸障碍相关的风险因素和预测因素.
- 为了识别感染后长期呼吸道症状的风险较高的个体.
主要方法:
- 按照PRISMA指导方针进行系统审查,并在PROSPERO.中进行前性注册.
- 在PubMed,CINAHL,Web of Science和EMBASE (2020年至2024年3月) 进行全面的文献搜索.
- 使用Covidence平台进行的数据提取和质量评估,经过独立审查.
主要成果:
- 包括33项研究,包括来自20个国家的83,920名参与者.
- 持续性呼吸不全的最强预测因素:女性性别,体重指数升高,肺部并发症,先前存在的焦虑/抑郁症,COVID-19前的身体限制,COVID-19的严重程度和社会经济因素.
- 潜在的危险因素包括年龄较大,吸烟史和特定的COVID-19变种.
结论:
- 临床医生可以利用已识别的风险因素和潜在的生物标志物来积极识别有风险的个体.
- 早期识别有助于及时转诊,以预防呼吸障碍的预防和康复干预.
- 建议针对可修改风险因素的个性化管理计划用于COVID-19后呼吸障碍.
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