在非肥胖睡眠呼吸暂停患者中,喉喉逆流和上呼吸道阻塞模式
Fatih Gul1, Aslihan Ensari2, Mehmet Ali Babademez1
1Department of Otorhinolaryngology, Ankara Yıldırım Beyazıt University School of Medicine, Ankara, Turkey.
The Laryngoscope
|January 29, 2025
概括
喉回流 (LPR) 与非肥胖患者的阻塞性睡眠呼吸暂停 (OSA) 的舌头底部阻塞增加有关. 这一发现突显了OSA管理中的一个关键关联.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 睡眠医学 睡眠医学
- 胃肠病学 胃肠病学
背景情况:
- 阻塞性睡眠呼吸暂停 (obstructive sleep apnea,OSA) 是一种常见的睡眠障碍,其特征是重复的上呼吸道崩.
- 喉回流 (LPR) 是一种胃酸刺激喉和喉的情况.
- LPR和OSA之间的相互作用,特别是在非肥胖个体中,需要进一步调查.
研究的目的:
- 探索LPR与睡眠期间上呼吸道阻塞程度之间的关联.
- 专门研究在被诊断患有OSA的非肥胖患者中这种关系.
主要方法:
- 一项前性研究涉及105名非肥胖的成年OSA患者接受药物诱导睡眠内镜检查 (DISE).
- 使用反流症状指数和反流发现得分来评估LPR.
- 使用VOTE分类系统和桃体缩分级来评估气道阻塞.
主要成果:
- 几乎一半的患者 (48.57%) 呈现LPR.
- 在LPR和舌头底部阻塞之间发现了显著的相关性 (p=0.039).
- 完整的舌头底部阻塞强烈预测了LPR的存在 (OR=10.227,p=0.007).
结论:
- 在非肥胖的OSA患者中,LPR与舌头底部阻塞的更高概率显著相关.
- 这表明,LPR可能是这个人群中舌头底部呼吸道崩的一个因素.
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