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开发一种新的核酸疗法,旨在直接控制肝纤维化

Tomohiro Umezu1, Masakatsu Takanashi2, Koji Fujita1

  • 1Department of Molecular Pathology, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan.

Molecular therapy. Nucleic acids
|January 29, 2025
PubMed
概括

一种基于miR-29a-3p的新型改性核酸有效治疗小鼠肝纤维化. 这种口服疗法在没有药物输送系统的情况下有望抑制肝纤维化进展.

关键词:
MT:寡核酸:治疗方法和应用.慢性肝损伤 慢性肝损伤药物输送系统是药物输送系统.肝脏纤维化 肝脏纤维化这是一个小RNARNA.修改过的寡核化物.通过口服进行口服管理.

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