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Updated: May 30, 2025

Whole-animal Imaging and Flow Cytometric Techniques for Analysis of Antigen-specific CD8+ T Cell Responses after Nanoparticle Vaccination
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一种基于物理学的神经网络方法来量化单细胞水平的抗原呈现活动,使用omics数据

Chi Zhang1, Jia Wang2, Pengtao Dang3

  • 1Indiana University School of Medicine.

Research square
|January 29, 2025
PubMed
概括

我们开发了PSAA,这是一种新的系统生物学工具,用于从omics数据中量化主要基因相容性复合 (MHC) 抗原呈现活性. 这种方法增强了对癌症和感染等疾病的免疫反应的理解.

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相关概念视频

Antigen Presenting Cells01:22

Antigen Presenting Cells

The immune system is a complex network of cells and molecules that protects the body from foreign invaders. T cells, a type of white blood cell, play a crucial role in this process. They recognize and attack foreign substances, such as pathogens, that enter the body.
T cells require the help of antigen-presenting cells (APCs), which process foreign antigens into smaller fragments that can be recognized by T cells. These APCs are highly specialized cells that efficiently internalize antigens...
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