跨性别成年人中的不良童年经历和主观认知衰退
Jobina Chiow1, Ethan C Cicero1
1Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA.
概括
童年不良经历 (ACE) 在跨性别和非二进制 (TGN) 成人中显著增加主观认知衰退 (SCD) 的风险. 早期查和创伤相关的护理对于减轻这些风险和支持大脑健康至关重要.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 社会科学 社会科学 社会科学
背景情况:
- 儿童不良经历 (ACE) 与慢性健康问题有关,包括阿尔茨海默病和相关痴呆症 (ADRD).
- 主观认知衰退 (SCD) 是ADRD的早期指标.
- 虽然ACE和SCD已在跨性别和非二进制 (TGN) 成人中单独研究,但它们之间的关系在这个人群中仍然未被探索.
研究的目的:
- 为了确定TGN成年人中ACE的患病率.
- 检查TGN成年人ACE和SCD之间的关联.
主要方法:
- 2019-2021年美国16个州的行为风险因素监测系统数据的二次分析.
- 包括45岁以上的TGN成年人 (N=206).
- 统计测试 (皮尔森的奇平方/费舍尔的精确) 和回归分析 (原始和调整的几率比率) 用于评估ACE和SCD之间的关联.
主要成果:
- 18%的TGN成年人报告SCD.
- 60%的人至少经历过一次ACE,近50%的人报告童年虐待或家庭功能障碍.
- 包括童年虐待和家庭功能障碍在内的ACE与增加SCD风险显著相关.
- 随着每次增加ACE (aOR=1.4),SCD的几率增加了40%.
结论:
- ACEs是TGN成年人中SCD的重要危险因素.
- 确认性别和创伤的护理,以及对ACE和SCD的查和干预,对于改善TGN成人健康和降低ADRD风险至关重要.
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