干预措施是为了减少社区药房在社区药房的非处方抗菌药物的销售
Moe Moe Thandar1, Toshiaki Baba1,2, Sadatoshi Matsuoka1
1Bureau of International Health Cooperation, National Center for Global Health and Medicine, Shinjuku-ku, Japan.
减少无处方抗微生物药物销售的干预措施的有效性有限. 多组件干预可能不会显著降低销售额,需要更多的研究来确定关于抗微生物药物管理的明确发现.
科学领域:
- 公共卫生 公共卫生
- 制药科学 制药科学
- 传染性疾病 传染性疾病
背景情况:
- 抗菌素耐药性 (AMR) 是一个重大的全球健康挑战.
- 不适当使用抗微生物药物,特别是非处方药的销售,推动了AMR.
- 社区药房是无处方抗菌药物销售的主要来源.
研究的目的:
- 评估旨在减少药剂师和非药剂师无处方抗菌药物的销售的干预措施.
- 为了确定干预效应是否因干预类型,人员或国家收入水平而有所不同.
主要方法:
- 随机化,集群随机化和准随机化试验的系统审查.
- 搜索了多个数据库和试验注册到2022年9月.
- 包括专注于社区药房,药店和药品商店干预措施的研究.
主要成果:
- 包括4项涉及942家药房的试验.
- 对单组件干预措施的证据有限.
- 多组件干预表明,非处方药销售的潜在但不确定的减少;证据确定性非常低.
- 在一些研究中,记录病史和提供咨询的改善得到了注意,但不总是如此.
结论:
- 由于证据有限,对单组件干预措施不能得出坚定的结论.
- 多组件干预措施可能无法有效减少非处方抗菌药的销售,证据确定性非常低.
- 进一步的研究是必不可少的,专注于制药政策和具体干预措施.
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