电子烟是用于戒烟的电子烟
Nicola Lindson1, Ailsa R Butler1, Hayden McRobbie2
1Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
The Cochrane database of systematic reviews
|January 29, 2025
概括
与尼古丁替代疗法 (NRT) 和非尼古丁EC相比,含尼古丁的电子烟 (EC) 显著增加了戒烟率. 虽然通常是安全的,但需要更多的研究来充分评估长期的安全性.
科学领域:
- 公共卫生 公共卫生
- 临床试验 临床试验
- 基于证据的医学基于证据的医学.
背景情况:
- 电子烟 (EC) 是用于输送尼古丁的电子烟设备.
- 关于它们在戒烟方面的有效性和安全性,目前仍在进行辩论.
- 本综述是关于吸烟戒断EC的活体系统综述的更新.
研究的目的:
- 评估尼古丁ECs的安全性,耐受性和有效性,用于长期戒烟.
- 比较包括非尼古丁EC,其他戒烟疗法和没有治疗.
主要方法:
- 系统性审查包括随机对照试验 (RCT) 和不受控制的干预研究.
- 在主要数据库中进行的搜索截至2024年2月.
- 使用偏差风险和GRADE评估;对聚合数据进行元分析.
主要成果:
- 高确定性证据表明,尼古丁EC增加了戒烟率与NRT相比 (RR 1.59).
- 中等确定性证据表明,尼古丁EC增加了戒烟率,而非尼古丁EC则增加了戒烟率 (RR 1.46).
- 尼古丁EC和NRT/非尼古丁EC之间的不良事件 (AE) 率相似;低确定性证据表明AEs与行为支持相比较高.
结论:
- 尼古丁EC在戒烟方面是有效的,有高确定性证据支持其使用超过NRT.
- 没有发现严重危害的证据,但长期安全性需要进一步调查.
- 审查正在进行中,每个月都会进行搜索,以纳入新的证据.
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