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在体外和体外的CTC检测方法及其在瘤免疫治疗中的应用

Xiujie Sui¹, Jiahao Ji², Hongyi Zhang³

¹Department of Radiotherapy, Yantaishan Hospital, Shandong, China.

Journal of surgical oncology

|January 29, 2025

概括

循环瘤细胞 (CTC) 为早期癌症检测和治疗监测提供了宝贵的见解. 本综述探讨了最新的体内和体外CTC检测方法及其在优化瘤免疫治疗策略中的作用.

科学领域:

在瘤学瘤学.
生物医学工程生物医学工程

背景情况:

循环瘤细胞 (CTC) 从原发性瘤流入血液.
癌症特征细胞是癌症早期检测,诊断和治疗监测的关键生物标志物.
目前的CTC检测方法正在向更少侵入性和更精确的技术发展.

研究的目的:

审查和总结体内和体外循环瘤细胞 (CTC) 检测方法的最新进展.
讨论这些CTC检测方法在评估和优化瘤免疫治疗有效性的应用.
为临床实践提供有关瘤学中CTC分析的指导.

主要方法:

在体内CTC检测技术的概述.
在体外CTC检测技术的总结,包括各种测试平台.
分析使用CTC检测用于监测免疫治疗反应的研究.

主要成果:

与传统方法相比,CTC检测可以更早地识别恶性瘤.
动态监测CTC有助于优化临床治疗策略和评估免疫疗法的有效性.
各种体内和体外方法显示出改善CTC捕获和分析的前景.

结论:

循环瘤细胞检测是一种微创的方法,在瘤学中具有显著的潜力.
对于评估瘤免疫疗法的有效性,CTC分析越来越重要.
本综述提供了全面的概述,以支持癌症护理中的临床决策.

关键词:

在CTC中,使用CTC.检测方法检测方法瘤是一个瘤.瘤免疫疗法免疫疗法瘤治疗的治疗方法

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Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.