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在不同的临床环境中,与酒精相关的肝炎治疗的短期成本
Chi Mai Nguyen1, Jing Su1, Yang Li1
1Department of Biostatistics & Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana, USA.
酒精相关肝炎诊断后的直接成本很高,特别是在住院护理方面. 管理伴随性疾病显著影响医疗保健支出和患者的治疗结果.
科学领域:
- 肝病学和胃肠病学 肝病学和胃肠学
- 卫生经济学 卫生经济学
- 临床医学 临床医学
背景情况:
- 酒精相关性肝炎 (AH) 对死亡率和医疗保健支出构成重大挑战.
- 了解诊断后的即时成本对于有效的医疗保健政策和临床实践至关重要.
研究的目的:
- 通过门诊,急诊和住院诊断,在AH诊断后的30天内量化医疗费用.
- 调查并发诊断对与AH相关的医疗保健成本的影响.
主要方法:
- 使用非识别索赔数据 (2016-2023) 的回顾性队列研究.
- 对30天AH前后诊断的成本分析,经通货膨胀调整.
- 使用 Elixhauser 软件和多变量回归用于成本分析来识别并发症.
主要成果:
- 该研究包括34974名AH患者在门诊 (23%),急诊 (7.8%) 和住院 (69.2%) 设置中.
- 诊断后的费用大幅增加:门诊14%,急诊266%,住院治疗413%.
- 关键的住院成本驱动因素包括严重的肝病并发症,代谢综合征,肝移植和死亡率.
结论:
- 在AH诊断后立即的医疗费用是相当大的,特别是在住院护理方面.
- 高成本的并发症集群和死亡率与医疗保健支出大幅增加有关.
- 有效的并发症管理对于减轻AH患者护理成本至关重要.
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