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在体外膜氧化支持后与创伤相关的精神病理:系统性审查和元分析
Ashley Demory1, Elizabeth Broden2, Lucile Equey3
1Department of Internal Medicine and Department of Pediatrics, Yale School of Medicine, New Haven, CT, USA.
Perfusion
|January 29, 2025
概括
身体外膜氧化 (ECMO) 可以导致患者和家人出现严重的心理健康问题. 这项审查发现,受ECMO治疗影响的人群中,PTSD,焦虑和抑郁症的发病率很高.
科学领域:
- 关键护理医学 关键护理医学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 身体外膜氧化 (ECMO) 是一种拯救生命的干预措施,但与患者及其家人相当大的心理痛苦有关.
- 了解ECMO后精神疾病的患病率对于开发有针对性的支持至关重要.
研究的目的:
- 在成人和儿科ECMO幸存者及其家人中系统地审查和量化创伤后应激障碍 (PTSD),焦虑和抑郁症的患病率.
- 为了确定与ECMO治疗相关的心理负担.
主要方法:
- 对ECMO患者或他们的家属中创伤相关的精神病理学报告的研究进行系统审查和元分析.
- 包括55项研究,5146名参与者,专注于成人和儿科ECMO幸存者和家庭成员.
主要成果:
- 在ECMO幸存者及其家人中发现了:PTSD (19-25%),焦虑 (8-67%) 和抑郁 (8-50%).
- 儿童幸存者和成年患者的家属报告了特别高的焦虑和抑郁率.
结论:
- 在幸存者和他们的家人中,ECMO的使用与创伤相关的精神病理的高患病率有关.
- 显然需要进行干预措施,以减轻ECMO治疗后的心理影响并改善长期结果.
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Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
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Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
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