肝移植接受者中痴呆症:使用MarketScan进行的国家分析
Jessica M Ruck1, Maria A Parra1, Matthew D Price1
1Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
The Journal of surgical research
|January 29, 2025
概括
在肝移植 (LT) 接受者中, Delirium 索赔很少见,仅影响 1.6% 的患者. 这种报告不足突出了需要改善在LT护理中的妄想识别和报告.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 临界护理医学 临界护理医学
- 神经科学是一个神经科学.
背景情况:
- 狂妄症是肝移植 (LT) 后经常出现的并发症.
- 之前关于LT后妄想的研究主要利用单中心数据.
- 需要进行一项国家队列研究,以了解LT接受者的妄想患病率和结果.
研究的目的:
- 调查成年肝移植接受者全国队列中 Delirium 的发病率和特征.
- 为了比较肝移植接受者与 Delirium 和没有 Delirium 之间的结果.
- 评估妄想对住院时间,费用和再入院率的影响.
主要方法:
- 利用MarketScan数据库识别2015年10月至2020年12月的成年肝移植接受者.
- 雇员要求数据以识别被诊断患有 Delirium 的肝移植接受者.
- 进行了描述性的统计分析,以比较有 Delirium 和没有 Delirium 的受试者的特征和结果.
主要成果:
- 只有1.6% (32在2051) 的肝移植接受者有 Delirium 索赔.
- 狂妄症与脑病史 (21.9%与8.2%,P=0.006) 相关.
- 患有妄想症的受试者在技术护理机构的出院率较高 (37.5%对14.3%,P=0.003),住院时间中位数较长 (24对14天,P=0.03).
结论:
- 妄想声称的低率 (1.6%) 与单中心研究中更高的患病率估计 (高达47%) 相反.
- 这种报告不足可能意味着,只有最严重的妄想病例被捕获在索赔数据中.
- 改善妄的识别和报告对于准确评估肝移植接受者的结果至关重要.
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