肺癌切除术后阿片类药物处方补充的预测因素
Lisa M Brown1, Journne Herrera1, Maricruz Diagut1
1Division of General Thoracic Surgery, Department of Surgery, University of California, Davis Health, Sacramento, California.
The Journal of surgical research
|January 29, 2025
概括
接受切除的阿片类药物原始肺癌患者面临高持续性阿片类药物使用. 与他人一起生活,胸切除术,更长的胸管持续时间,年龄较大,以及更高的放出阿片类药物剂量预测出院后的补充.
科学领域:
- 胸部外科手术 胸部外科手术
- 在瘤学瘤学.
- 疼痛管理 疼痛管理
背景情况:
- 胸部手术患者在手术后出现新的持续性阿片类药物使用的发病率很高.
- 肺癌切除患者,特别是,显示近27%的新持续阿片类药物使用者率.
- 识别阿片类药物处方补充的风险因素对于管理出院后的疼痛管理至关重要.
研究的目的:
- 为了确定与阿片类药物处方相关的风险因素,肺癌切除手术后90天内补充.
- 在这个患者群体中,为优化阿片类药物处方实践制定策略.
主要方法:
- 之前未服用过阿片类药物的患者接受肺癌切除术的回顾性队列研究.
- 在学术医疗中心从2018年7月到2021年5月收集的数据.
- 多变量后勤回归分析以确定阿片类药物处方补充的重大风险因素.
主要成果:
- 包括152名患者;19.1%的患者在出院后经历了阿片类药物处方补充.
- 重灌的关键风险因素包括与家人/朋友住在一起 (aOR 5.31),胸切除术 (aOR 4.31),胸管持续时间长 (aOR 1.14 每天),年龄越来越大 (aOR 1.08) 和离院时更高的吗啡毫克相当量 (MME) (aOR 1.07).
结论:
- 生活状况,手术方法 (胸切除术),胸管持续时间,患者年龄和离院前阿片类药物MME是肺癌切除患者离院后阿片类药物补充的重要预测因素.
- 这些确定的因素可以指导更个性化和明智的阿片类药物处方,以减轻长期阿片类药物使用.
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