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Updated: May 30, 2025

In Vitro Analysis of E3 Ubiquitin Ligase Function
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孤儿质量控制途径在无素链延长联酶的融合

Sara Carrillo Roas1, Yuichi Yagita1, Paul Murphy2

  • 1MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

Molecular cell
|January 29, 2025
PubMed
概括

UBR4-KCMF1复合体降解了对细胞健康至关重要的孤儿蛋白质子单元. 这一发现揭示了蛋白质质量控制的关键机制以及癌细胞的脆弱性.

关键词:
E3 结合酶的使用在KCMF1中,KCMF1是这就是UBR4 UBR4.蛋白质质量控制 蛋白质质量控制蛋白质稳定性 蛋白质稳定性无处不在的化

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