在 podocytes 中依赖 REDD1 的 GSK3β 信号传递促进了糖尿病病症中正规的 NF-κB 激活

Siddharth Sunilkumar1, Esma I Yerlikaya1, Ashley VanCleave1

  • 1Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania, USA.

概括

糖尿病病症涉及增加的免疫反应. 压力蛋白REDD1激活GSK3β,通过NF-κB信号促进炎症,导致糖尿病损伤.

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