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Updated: May 30, 2025

Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
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在多层自我纳米乳化颗粒中的物理隔离策略:改善拉米的溶解和药物加载效率

Ahmad Abdul-Wahhab Shahba1, Abdelrahman Y Sherif1, Ehab M Elzayat2

  • 1Department of Pharmaceutics, College of Pharmacy, King Saud University, POBOX-2457, Riyadh 11451, Kingdom of Saudi Arabia; Kayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia.

Journal of pharmaceutical sciences
|January 29, 2025
PubMed
概括

这项研究开发了多层自我纳米乳化颗粒 (ML-SNEP),以提高拉米普里尔 (RMP) 和提摩 (THQ) 的稳定性和溶解性. 新的颗粒配方提高了药物加载效率,同时保持了药物快速释放,提供了一个有前途的口服输送系统.

关键词:
开发和优化开发和优化流体床涂层是一种流体床涂层.多颗粒系统是多颗粒系统.拉米普利尔是什么意思拉米普利尔是什么意思固体SNEDDS是什么意思

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