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Updated: May 30, 2025

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通过人类血清白蛋白抑制粉样蛋白的捕获和聚合

Diego Cora1, Wajih Al-Soufi1, Mercedes Novo1

  • 1Departamento de Química Física, Facultade de Ciencias, Campus Terra, Universidade de Santiago de Compostela, 27002 Lugo, Spain.

International journal of biological macromolecules
|January 29, 2025
PubMed
概括

人类血清白蛋白 (HSA) 有效地结合和分解与阿尔茨海默病 (AD) 相关的粉样ββ (Aβ) . 这种相互作用显示了减少大脑Aβ积累的治疗潜力.

关键词:
聚合 聚合 是一种聚合.阿尔茨海默氏症的疾病是阿尔茨海默氏症.粉样蛋白是什么 粉样蛋白是什么在FCS中使用FCS.光是一种光效应.光相关谱法 光相关谱法在HSA中,HSA就是HSA.人类血清专素的人类血清专素超分子关联是超分子的关联.

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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