从1990年到2021年,亚洲的鼻癌的负担
Meimei Cui1, Huijuan Cheng2, Linlin Yuan3
1Maternal and Child Health Development Research Center, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, Shandong 250014, PR China; Department of Clinical Pathology, School of Basic Medicine, Shandong Second Medical University, Weifang, Shandong 261053, PR China.
Journal of dentistry
|January 29, 2025
概括
鼻癌 (NPC) 仍然是亚洲,特别是东亚的重大健康负担. 人口增长和行为风险是关键驱动因素,需要有针对性的预防和控制策略.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 鼻癌 (NPC) 在亚洲呈现出相当大的疾病负担.
- 了解NPC的区域差异和趋势对于公共卫生干预至关重要.
研究的目的:
- 通过2021年全球疾病,伤害和风险因素研究 (GBD) 的数据,调查亚洲鼻癌 (NPC) 的疾病负担.
- 分析亚洲NPC负担的趋势,驱动因素和未来预测.
主要方法:
- 利用GBD 2021数据评估亚洲的NPC发病率,死亡率和残疾调整寿命年 (DALYs) 根据性别和年龄.
- 用于趋势分析和分解分析的雇员估计年百分比变化 (EAPC),以确定NPC负担的驱动因素.
- 评估的DALY归因于可修改的风险因素和预计的NPC负担到2044年.
主要成果:
- 在2021年,亚洲记录了超过101,841个事件病例,62,079例死亡,以及2,041,239个DALY由于NPC.
- 从1990年到2021年,NPC的年龄标准化利率 (ASR) 呈现下降趋势,东亚承担了最大的负担.
- 中国和印度面临着严重的NPC负担. 中亚地区的ASIR和ASMR呈现上升趋势,而亚美尼亚的ASR增长最快. 人口增长和行为风险被确定为主要驱动因素.
结论:
- 在亚洲,特别是东亚,NPC仍然是一个重要的公共卫生问题,中国和印度面临着人口老龄化和增长带来的挑战.
- 亚美尼亚日益增加的NPC发病率需要紧急关注.
- 针对高风险地区的有针对性的预防和控制政策,加上减轻行为风险因素的努力,对于管理NPC负担至关重要.
相关概念视频
01:29Suctioning the Nasopharyngeal Airway
251
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Equipment Required
251
01:21Cancer Survival Analysis
324
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
324
01:05Single Nucleotide Polymorphisms-SNPs
13.9K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
13.9K
02:07Tumor Progression
6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K
01:03Rous Sarcoma Virus (RSV) and Cancer
4.9K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
4.9K
01:23Chronic Pharyngitis
1.0K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
1.0K