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Updated: May 12, 2026

Recording and Analysis of Circadian Rhythms in Running-wheel Activity in Rodents
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评估数字通风®系统用于昼夜表型

Selma Tir1, Russell G Foster1, Stuart N Peirson2

  • 1Sir Jules Thorn Sleep and Circadian Neuroscience Institute, Kavli Institute for Nanoscience Discovery, Nuffield Department of Clinical Neurosciences, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford, OX1 3QU, UK.

Scientific reports
|January 29, 2025
PubMed
概括

数字通风 (DVC) 系统有效地监测小鼠在各种照明条件下的昼夜节律和活动. 这种新的方法准确地检测了野生类型和缺乏时钟的小鼠的昼夜周期,中断和相位变化.

关键词:
循环节律的破坏.循环时间的表型化.循环节的屏幕显示时间.在家监控子监控.个别通风的子单独通风.运动机动活动 运动机动活动

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Circadian Rhythms and Gene Regulation02:19

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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent years,...