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Updated: May 30, 2025

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
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对效应体 γδ T 细胞的特征细胞因子相关转录组分析确定了外围激活子集特定的调节者

Daniel Inácio1,2, Tiago Amado1, Ana Pamplona1

  • 1Gulbenkian Institute for Molecular Medicine, Lisbon, Portugal.

Nature immunology
|January 29, 2025
PubMed
概括

研究人员在外围马三角形T细胞子集中发现了新的特征基因. 发现CD6和Themis促进了玛三角T细胞的激活和增殖,有助于理解免疫反应.

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相关概念视频

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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