在积极治疗后,低风险乳腺癌幸存者经历的持续症状和担忧
Jessica R Schumacher1,2, Jennifer L Tucholka1, Catherine R Breuer1
1Department of Surgery, School of Medicine and Public Health, Wisconsin Surgical Outcomes Research Program, University of Wisconsin, Madison, WI, USA.
Annals of surgical oncology
|January 29, 2025
概括
早期乳腺癌幸存者经历了显著的症状负担,许多人报告了多个问题. 患者报告的结果 (PRO) 对于识别未满足的需求和改善幸存者护理至关重要.
科学领域:
- 在瘤学瘤学.
- 癌症的生存率 癌症的生存率
- 患者报告的结果
背景情况:
- 对早期乳腺癌幸存者的症状负担的理解有限,特别是那些没有接受化疗的人.
- 激素受体阳性,HER2阴性早期乳腺癌的化疗使用减少,需要对症状经验进行最新的研究.
- 现有研究可能无法反映当前的患者群体,因为像型DX.这样的进步.
研究的目的:
- 评估早期乳腺癌幸存者所经历的症状负担.
- 为了确定这一群体中临床显著症状的患病率.
- 通过了解幸存者的需求,为改善幸存者护理提供信息.
主要方法:
- 研究包括了I-II,ER+/PR+,HER2-乳腺癌的幸存者,诊断后6个月至5年,没有化疗.
- 通过电子邮件管理的患者报告结果 (PRO) 调查,通过生存指南和利益相关方的意见提供信息.
- 根据调查反应报告了临床显著症状的患病率.
主要成果:
- 98名早期乳腺癌幸存者参与了这项研究.
- 大多数幸存者 (86.2%) 报告出现症状,其中47.9%报告超过三个症状.
- 平均年龄为61.3岁,诊断后的平均时间为2.5年.
结论:
- 早期乳腺癌幸存者面临着相当大的症状负担,通常超过三个症状.
- 时间有限的随访可能无法充分解决幸存者症状的范围,包括性健康等敏感问题.
- 利用PRO对于全面评估和解决幸存者护理中未知的需求至关重要.
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