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Updated: May 30, 2025

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
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A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

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开发基于Soluplus®的微粒无形固体分散剂,具有高药物负载,用于通过电子喷射增强切莱可西布溶解

Fan Fan1,2, Feng Zhou1,2, Jiayu Zhang3

  • 1Laboratory of Advanced Theranostic Materials and Technology, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, 315201, China.

AAPS PharmSciTech
|January 29, 2025
PubMed
概括

电喷剂制造了稳定的无形固体分散 (ASD) 赛莱科西布 (CEL) 和Soluplus® (SOL) 具有高药物负载. 这些微粒子ASD显著增强了CEL溶解,为水溶性较差的药物提供了有希望的替代品.

关键词:
无形固体分散 (ASDs) 是一种无形固体分散.电气喷是一种电子喷.大量的毒品负载.可溶性增强 提高可溶性这是基于soluplus®的微粒.

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