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Updated: May 30, 2025

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在外置工程中,使用构造强化抗体对卡德林内细胞结合的工程使用构造强化抗体

Bin Xie1, Shipeng Xu2, Sanjeevi Sivasankar3,4

  • 1Biophysics Graduate Group, University of California, Davis, CA, USA.

Nature communications
|January 29, 2025
PubMed
概括

针对P-cadherin的抗体可以通过将其困在X-二次体构造中来触发其内部化. 这种机制涉及p120-catenin酸化,使得针对癌症治疗的细胞内药物提供成为可能.

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