ADSL通过以烟酸为媒介的Beclin1二甲基化促进了自和瘤生长

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Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy
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Lei Wang1,2,3, Runze Shi4, Shuo Wang5

  • 1Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, China.

Nature chemical biology
|January 29, 2025
PubMed
概括

腺酸酶 (ADSL) 通过增强自促进肝癌. 通过PERK对ADSL的酸化激活了一条增加自的途径,促进瘤生长和肝细胞癌的不良预后.

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