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Updated: May 30, 2025

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6 - 瓜氨酸通过降低BIRC3介导的自酶来抑制EV71的复制

Qiao You1, Jing Wu1,2, Ruining Lyu1

  • 1Center for Public Health Research, Medical School of Nanjing University, Nanjing, China.

BMC microbiology
|January 29, 2025
PubMed
概括

6 - 提奥瓜宁 (6-TG) 有效地抑制了肠道病毒71 (EV71) 在细胞中的复制. 这种FDA批准的药物对EV71表现出强大的抗病毒活性,这表明它有可能治疗手足口病 (HFMD).

关键词:
6 - 硫氨酸 (6-TG) 是一种自自是一种自的过程.在BIRC3中,你会发现BIRC3是什么.在EV71中使用EV71

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Leaky Scanning02:28

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R...
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