患者作为医疗数字双胞胎的数字表现:以数据为中心的观点
Stanislas Demuth1,2, Jérôme De Sèze2,3, Gilles Edan4
1INSERM U1064, CR2TI - Center for Research in Transplantation and Translational Immunology, Nantes University, 30 Bd Jean Monnet, Nantes, 44093, France, 33 2 40 08 74 10.
JMIR medical informatics
|January 29, 2025
概括
这项研究提出了一个新的医疗数字双胞胎框架,使用以数据为中心的方法. 它表明需要多个患者表征用于不同的用途,超越单个数字模型.
科学领域:
- 生物医学信息学 生物医学信息学
- 健康 数据科学 数据科学
- 计算医学是一种计算医学.
背景情况:
- 精准医学强调个性化,数据驱动的临床决策.
- 医疗数字双胞胎概念在数据科学应用中越来越受欢迎.
- 目前医疗数字双胞胎的实施缺乏清晰度和标准化.
研究的目的:
- 提出一个新的医疗数字双胞胎框架.
- 为了解决单个患者数字化代表的模糊性和技术/监管挑战.
- 为各种数字生应用建立一个以数据为中心的架构.
主要方法:
- 为医疗数字双胞胎开发了一个以数据为中心的框架.
- 提出了一个数据架构,包含三个数字表示家族:多式联络仪表板,虚拟患者和个人预测.
- 强调将表示量身定制到特定的临床途径和预期用途.
主要成果:
- 反对所有数据用途的单一数字表示.
- 引入了一个利用多个,专门的数字患者表示的框架.
- 强调需要在框架内平衡不同数据用途的权衡.
结论:
- 医疗数字双胞胎应该被概念化为一个数据架构.
- 多个,路径特定的数字表示对于有效的医疗数字双胞胎至关重要.
- 该框架通过专门的患者数据模型支持医疗保健中的各种数据科学应用.
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