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Ravinder Kaur¹, Deepti Rawat¹, Ashish William¹

¹Department of Microbiology, Lady Hardinge Medical College & Associated Hospitals, New Delhi, Delhi, India.

Access microbiology

|January 30, 2025

概括

在COVID-19大流行期间,机会性真菌感染的数量显著增加. 在COVID-19患者中,真菌培养更频繁地呈阳性,Candida,Aspergillus和Mucor物种最常见.

科学领域:

医学真菌学医学真菌学
传染性疾病传染性疾病
关键护理医学关键护理医学

背景情况:

冠状病毒疾病2019 (COVID-19) 流行病与机会性侵入性真菌感染的增加有关,特别是在重症或免疫功能低下的患者中.
菌共同感染构成了重大的临床挑战,可能会使患者的治疗结果恶化.

研究的目的:

在COVID-19大流行期间调查患者的真菌感染的流行率和类型.
分析来自COVID-19阳性和COVID-19阴性患者的各种临床标本的真菌分离物.

主要方法:

对疑似真菌感染的患者的临床样本进行了回顾性分析.
从包括尿液,血清,呼吸道分泌物,鼻腔和组织样本在内的样本进行真菌培养和鉴定.
在COVID-19阳性和COVID-19阴性患者组之间的真菌隔离率的比较.

主要成果:

在64%的COVID-19阳性患者中,真菌培养是阳性的,而在COVID-19阴性患者中,这一比例为43%.
从COVID-19患者中分离出来的最常见的真菌是Candida spp. (63%),阿斯伯吉勒斯种类 (Aspergillus spp.) 的人类. (15%),以及Mucor spp. 的种类. (6%) 的情况.
在COVID-19阳性患者的尿液 (27%) 和呼吸道样本 (15%) 中经常隔离Candida物种.

结论:

在COVID-19大流行期间,真菌共同隔离的数量显著增加,这突显了严重的公共卫生问题.
临床症状与实验室真菌隔离之间的相关性对于及时诊断和有效管理这些感染至关重要.
早期检测和管理COVID-19患者的真菌感染对于改善患者预后至关重要.

关键词:

在CAM (Covid-19相关的粘膜菌症) 中.阿斯珀吉洛斯症 (aspergillosis) 是一种疾病.候选症候群病是一种候选症.粘膜性肌肉病的发生.

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