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Updated: May 30, 2025

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
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MAPK向瓜核酸交换因子GEF-H1发出信号的动态合

Kévin Leguay1, Oliver A Kent1

  • 1Department of Pharmacology, adMare BioInnovations, Montréal, Quebec, H4S 1Z9, Canada.

OncoTargets and therapy
|January 30, 2025
PubMed
概括

在胰腺癌中,GEF-H1通过将PP2A与KSR-1进行支架来强化MAPK信号传递. 抑制GEF-H1可能为RAS驱动的癌症提供一种新的治疗策略.

关键词:
时间2 ARHGEF2在GEF-H1中,GEF-H1是指GEF.这是RAS-MAPK.一个RREBEB1一个RREBEB1在RhoAAA胰腺 胰腺 胰腺 胰腺

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