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Updated: May 30, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors

Published on: May 9, 2025

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关于DDR抑制剂的解释性综述:它们的生物活性,合成途径和结构-活性关系关系

Sindhuja Sengupta1,2, Lalmohan Maji1,3, Pronoy Kanti Das1

  • 1Integrated Drug Discovery Centre, Department of Pharmaceutical Chemistry, Acharya & BM Reddy College of Pharmacy, Bengaluru, 560107, Karnataka, India.

Molecular diversity
|January 30, 2025
PubMed
概括

迪斯科伊丁域受体 (DDR) 是关键的氨酸激酶受体,与癌症和纤维化等疾病有关. 本综述详细介绍了DDR结构,信号传递和抑制剂,重点介绍了强效化合物64a和103a.

关键词:
在DDR1和DDR2中.分子对接研究分子对接研究.选择性的选择性结构活动关系结构活动关系合成途径 合成途径

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