患者和护理人员对CAR T细胞治疗的经验:定性分析
Maija Reblin1, Irene Liang2, Djin L Tay3
1Department of Family Medicine, University of Vermont, Burlington, VT, USA.
Journal of psychosocial oncology
|January 30, 2025
概括
卡特-T疗法需要密集的护理人员支持,影响患者和家人身体和关系. 成本和物流等社会因素也使这种新的癌症治疗体验变得复杂.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 患者护理 患者护理
背景情况:
- 化学抗原受体T细胞 (CAR-T) 疗法为某些癌症提供了新的希望.
- 在注射后,CAR-T治疗需要大量的家庭护理人员参与.
- 了解患者和护理人员对CAR-T的体验是非常重要的,因为它是新的.
研究的目的:
- 探索接受CAR-T治疗的患者及其护理人员的实践经验.
- 确定患者和护理人员在CAR-T治疗过程中所面临的关键主题和挑战.
主要方法:
- 定性研究涉及与CAR-T患者及其护理人员进行半结构面试.
- 采访成绩单的分析,以双癌症结局框架为指导.
- 诱导性主题分析,以确定患者和护理人员经验中的反复模式.
主要成果:
- 出现了三个主要主题:个人 (身体/心理社会影响),关系 (照顾者对关系的压力) 和情境 (社会/金融挑战).
- 卡特治疗显著影响了患者和护理人员的福祉.
- 退院后护理的密集,孤立的性质加剧了患者和护理人员关系的动态.
结论:
- 患者和护理人员的CAR-T体验与其他癌症治疗有相似之处,但由于不断的护理需求而加剧.
- 住房,旅行和财务等社会决定因素带来了重大障碍.
- 开发以家庭为中心的支持计划对于优化CAR-T治疗结果至关重要.
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