在格鲁吉亚-A基于出生登记册的队列研究中,怀孕期间的贫血和母亲的不良结果
Natia Skhvitaridze1,2,3, Amiran Gamkrelidze3, Tinatin Manjavidze1,2,3
1Department of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
PloS one
|January 30, 2025
概括
贫血影响了格鲁吉亚三分之一的孕妇,地区的流行率各不相同. 第三个三个月的贫血并没有显著增加ICU入院或早产的风险,但需要多方面的干预措施.
科学领域:
- 产科和妇科 产科和妇科
- 公共卫生 公共卫生
- 血液学 血液学 血液学
背景情况:
- 怀孕期间的贫血是一个重要的全球公共卫生问题.
- 关于格鲁吉亚贫血患病率和结果的研究有限.
- 这项研究解决了关于格鲁吉亚孕妇贫血症的知识差距.
研究的目的:
- 为了确定在格鲁吉亚孕妇中贫血的流行率.
- 调查第三季度贫血与母亲不良后果之间的关联,包括ICU入院和早产.
主要方法:
- 使用了格鲁吉亚出生登记处 (n=158,668) 的数据,用于2019年1月至2022年8月间的分娩.
- 计算区域性贫血患病率 (血红蛋白<110 g/L) 和根据世卫组织季度特异性值进行严重程度分类.
- 进行了后勤回归来评估贫血状况与分娩后ICU入院和早产之间的关联.
主要成果:
- 整体贫血患病率为33.1%,区域差异很大 (19.2%-32.8%).
- 在第三季度,71.0%没有贫血,20.9%轻度,8.1%中度/重度.
- 贫血严重程度并没有显示ICU入院几率的线性增加 (P=.13) 但显示出早产的逆趋势 (P=.01).
结论:
- 格鲁吉亚有很大比例的孕妇患有贫血症,在不同地区的患病率上存在差异.
- 第三个三个月的贫血与增加母亲ICU入院或早产的几率没有很强的关联.
- 解决怀孕期间的贫血症需要全面的管理和对潜在因素的调查,以实现可持续发展目标.
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