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Updated: May 30, 2025

Initiating Differentiation in Immortalized Multipotent Otic Progenitor Cells
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Initiating Differentiation in Immortalized Multipotent Otic Progenitor Cells

Published on: January 2, 2016

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对于内毛细胞命运稳定和外毛细胞存活,Casz1是必需的

Yuwei Sun1,2, Minhui Ren1,2, Yu Zhang3,4

  • 1Institute of Neuroscience, State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.

Science (New York, N.Y.)
|January 30, 2025
PubMed
概括

在发育过程中,转录因子Casz1对于稳定内毛细胞 (IHC) 标识和外毛细胞 (OHC) 存活至关重要. Casz1的损失导致IHC变成OHC,影响听力和毛细胞再生潜力.

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