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Updated: May 11, 2026

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis
07:45

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis

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免疫检查点抑制剂通过通过cGAS/STING通路促进巨细胞极化来调解心肌炎

Zhenzhu Cao1, Yu Zhang1, Huihui Jia1

  • 1Department of Cardiology, Nanjing Drum Tower Hospital, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, 358 Zhongshan Road, 210008 Nanjing, China.

Cytokine
|January 30, 2025
PubMed
概括

免疫检查点抑制剂可以通过激活cGAS-STING通路引起心肌炎. 这一途径导致巨细胞两极分化和自身免疫性心脏炎症,突出了一个新的治疗点.

关键词:
巨细胞的两极分化线粒体损伤,线粒体损伤,心肌炎,心肌炎,刺,刺,刺,刺,刺,刺,刺

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Isolation of Macrophage Subsets and Stromal Cells from Human and Mouse Myocardial Specimens

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