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从河流到地下水:抗生素污染,耐药性流行,以及来源追踪

Dailing Wu¹, Hong Bai², Liang-Ying He²

¹School of Environment, South China Normal University, University Town, Guangzhou, China; Aquatic Ecology and Water Quality Management Group, Wageningen University & Research, Wageningen, the Netherlands; Laboratory of Microbiology, Wageningen University & Research, Wageningen, the Netherlands.

Environment international

|January 30, 2025

概括

毛州河中的抗生素残留物构成生态风险,并有助于地下水中的抗菌素耐药性. 河流污染严重影响地下水质量,突出了改善环境管理的必要性.

科学领域:

环境科学环境科学
微生物学微生物学
公共卫生公共卫生

背景情况:

由于广泛使用,抗生素残留物在环境中普遍存在.
关于地下水污染和因河流污染而产生的相关风险的数据有限.
城市河流污染对连接的地下水生态系统的影响尚不清楚.

研究的目的:

评估毛州河和地下水中抗生素的生态和健康风险.
确定大肠杆菌中抗菌素耐药性的流行率和类型.
在地下水中追踪抗生素耐药性基因 (ARG) 的来源.

主要方法:

使用LC-MS/MS和16S rRNA测序分析了45种抗生素和微生物群落.
在潮湿和干旱季节对沉积物,地表水和地下水进行采样.
对大肠杆菌的隔离和耐药性分析,包括针对ARG的PCR和SourceTracker分析.

主要成果:

河流和沉积物中的多种抗生素对藻类和细菌耐药性构成高风险.
地下水表现出特定抗生素 (erythromycin,norfloxacin) 的中低风险.
细菌类和抗生素之间的显著相关性表明社区组成的影响;大肠杆菌的74%是耐药的,7.9%是多药耐药的.

结论:

河流污染直接影响地下水质量,增加抗生素残留物和抗菌素耐药性.
浅地下水的ARG来源于河流沉积物;较深的地下水来自河水.
解决河流污染问题对于保护受污染地区地下水质量至关重要.

关键词:

抗生素抗生素是一种抗生素.抗生素耐药性抗生素耐药性埃舍里希亚大肠杆菌 (Escherichia coli) 是一个大肠杆菌.地下水的地下水.微生物社区的微生物社区.源追踪源追踪源追踪

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