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在药物发现中,基于生理学的药理动力学模型的现实应用

Laura G A Santos1, Swati Jaiswal1, Kuan-Fu Chen1

  • 1Simcyp Division, Certara UK, Ltd, Princeton, New Jersey.

Drug metabolism and disposition: the biological fate of chemicals
|January 30, 2025
PubMed
概括

基于生理学的药理动力学 (PBPK) 模型通过预测人体剂量,评估风险和指导候选人选择来帮助药物发现. 案例研究证明了PBPK的存在.

关键词:
药物相互作用 药物相互作用人类中的第一人.建模建模模型是什么药理动力学 药理动力学基于生理学的药物动力学.预测 预测 预测

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