心血管健康和骨质疏松性骨折之间的关联:一项基于全国人口的研究
Jun Ou1,2, Tingting Wang1, Ridan Lei1
1Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, NO. 172 Tong Zi Po Road, Yuelu District, Changsha, 410006, Hunan, China.
Scientific reports
|January 30, 2025
概括
保持良好的心血管健康 (CVH) 与较少的骨质疏松性骨折有关. 更高的生活必需品8 (LE8) 评分与美国成年人骨折风险降低相关,这表明综合健康策略.
科学领域:
- 心血管健康和骨质新陈代谢
- 老年医学 老年医学
- 公共卫生流行病学 流行病学
背景情况:
- 骨质疏松性骨折构成了重大的公共卫生挑战,在老年人群中增加了发病率和死亡率.
- 心血管健康 (CVH) 传统上与心血管疾病有关,但新兴研究表明与骨健康有关.
- 生活必需品8 (LE8) 评分通过八个关键指标来衡量CVH.
研究的目的:
- 通过LE8评分评估的心血管健康 (CVH) 与美国成年人骨质疏松性骨折的患病率之间的关联.
- 为了确定CVH改善是否与骨质疏松性骨折风险降低有关.
- 探索对整合心血管和骨健康的公共卫生战略的影响.
主要方法:
- 使用2005-2018年国家健康和营养检查调查 (NHANES) 数据进行的横截面研究.
- 包括17,606名20岁以上的美国成年人,他们有CVH (LE8得分) 和骨质疏松性骨折的数据.
- 权重的多变量逻辑回归模型分析了相关性,并对共变量进行了调整.
主要成果:
- 较高的CVH得分与骨质疏松性骨折的患病率较低显著相关.
- 在LE8得分每增加1分,骨质疏松性骨折几率下降1% (OR=0.99).
- 与低CVH患者相比,中度和高CVH患者的骨折几率分别降低了22%和34%, (趋势P<0.001).
结论:
- 在美国成年人中,心血管健康和骨质疏松性骨折之间存在显著的反向联系.
- 通过LE8得分来衡量,保持最佳的CVH可能是减少骨折风险的关键因素.
- 针对心血管和骨健康的综合公共卫生战略可以改善整体健康状况,减少疾病负担.
关键词:
在CVH中,CVH是最重要的.LE8 LE8 LE8 LE8 LE8 LE8 LE8 LE8 LE8尼汉斯 (NHANES) 是一个名人.骨质疏松症是一种骨质疏松症.骨质疏松性骨折可能会导致骨折.更多相关视频
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